Toxicological Data on Ingredients: Acetic acid: ORAL (LD50): Acute: 3310 mg/kg [Rat]. 4960 mg/kg [Mouse]. 3530 mg/kg [Rat]. DERMAL (LD50): Acute: 1060 mg/kg [Rabbit]. VAPOR (LC50): Acute: 5620 ppm 1 hours [Mouse].
3: Hazards Identification
Potential Acute Health Effects: Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Hazardous in case of skin contact (corrosive, permeator), of eye contact (corrosive). Liquid or spray mist may produce tissue damage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.
Potential Chronic Health Effects: Hazardous in case of skin contact (irritant), of ingestion, of inhalation.
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to kidneys, mucous membranes, skin, teeth. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated
or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.
4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention immediately.
Skin Contact: In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.
Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate medical attention.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.
Serious Inhalation: Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 463°C (865.4°F)
Flash Points: CLOSED CUP: 39°C (102.2°F). OPEN CUP: 43°C (109.4°F).
Flammable Limits: LOWER: 4% UPPER: 19.9%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Flammable in presence of open flames and sparks, of heat. Slightly flammable to flammable in presence of oxidizing materials, of metals.
Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in presence of static discharge: Not available. Slightly explosive in presence of oxidizing materials.
Fire Fighting Media and Instructions: Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam, water spray or fog. Cool containing vessels with water jet to prevent pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards: Reacts with metals to produces flammable hydrogen gas. It will ignite on contact with potassium-tert-butoxide. A mixture of ammonium nitrate and acetic acid ignites when warmed, especially if warmed.
Special Remarks on Explosion Hazards: Acetic acid vapours may form explosive mixtures with air. Reactions between acetic acid and the following materials are potentially explosive: 5-azidotetrazole, bromine pentafluoride, chromium trioxide, hydrogen peroxide, potassium permanganate, sodium peroxide, and phosphorus trichloride. Dilute acetic acid and dilute hydrogen can undergo an exothermic reaction if heated, forming peracetic acid which is explosive at 110 degrees C. Reaction between chlorine trifluoride and acetic acid is very violent, sometimes explosive.
6: Accidental Release Measures
Dilute with water and mop up or absorb with an inert dry material and place in an appropriate waste disposal container. If necessary: Neutralize the residue with a dilute solution of sodium carbonate.
Flammable liquid. Corrosive liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. If the product is in its solid form: Use a shovel to put the material into a convenient waste disposal container. If the product is in its liquid form: Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Absorb with an inert material and put the spilled material in an appropriate waste disposal. Do not touch spilled material. Use water spray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Call for assistance on disposal. Neutralize the residue with a dilute solution of sodium carbonate. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
7: Handling and Storage
Precautions: Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this product. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, reducing agents, metals, acids, alkalis.
Storage: Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
8: Exposure Controls/Personal Protection
Engineering Controls: Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapours below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.
Personal Protection: Splash goggles. Synthetic apron. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves (impervious).
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits: TWA: 10 STEL: 15 (ppm) [Australia] TWA: 25 STEL: 27 (mg/m3) [Australia] TWA: 10 STEL: 15 (ppm) from NIOSH TWA: 25 STEL: 37 (mg/m3) from NIOSH TWA: 10 STEL: 15 (ppm) [Canada] TWA: 26 STEL: 39 (mg/m3) [Canada] TWA: 25 STEL: 37 (mg/m3) TWA: 10 STEL: 15 (ppm) from ACGIH (TLV) [United States]  TWA: 10 (ppm) from OSHA (PEL) [United States] TWA: 25 (mg/m3) from OSHA (PEL) [United States]Consult local authorities for acceptable exposure limits.
9: Physical and Chemical Properties
Physical state and appearance: Liquid.
odour: Pungent, vinegar-like, sour (Strong.)
Taste: Vinegar, sour (Strong.)
Molecular Weight: 60.05 g/mole
Colour: Colourless. Clear (Light.)
pH (1% soln/water): 2 [Acidic.]
Boiling Point: 118.1°C (244.6°F)
Melting Point: 16.6°C (61.9°F)
Critical Temperature: 321.67°C (611°F)
Specific Gravity: 1.049 (Water = 1)
Vapor Pressure: 1.5 kPa (@ 20°C)
Vapor Density: 2.07 (Air = 1)
Volatility: Not available.
odour Threshold: 0.48 ppm
Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.2
Iconicity (in Water): Not available.
Dispersion Properties: See solubility in water, diethyl ether, acetone.
Solubility: Easily soluble in cold water, hot water. Soluble in diethyl ether, acetone. Miscible with Glycerol, alcohol, Benzene, Carbon Tetrachloride. Practically insoluble in Carbon Disulphide.
10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Heat, ignition sources, incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, metals, acids, alkalis.
Corrosivity: Highly corrosive in presence of stainless steel (304). Slightly corrosive in presence of aluminium, of copper. Non-corrosive in presence of stainless steel (316).
Special Remarks on Reactivity: Reacts violently with strong oxidizing agents, acetaldehyde, and acetic anhydride. Material can react with metals, strong bases, amines, carbonates, hydroxides, phosphates, many oxides, cyanides, sulphides, chromic acid, nitric acid, hydrogen peroxide, carbonates. ammonium nitrate, ammonium thiosulfate, chlorine trifluoride, chlorosulfonic acid, perchloric acid, permanganates, xylene, oleum, potassium hydroxide, sodium hydroxide, phosphorus isocyanate, ethylenediamine, ethylene imine.
Special Remarks on Corrosivity: Moderate corrosive effect on bronze. No corrosion data on brass
Polymerization: Will not occur.
11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation. Ingestion.
Toxicity to Animals: WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE. Acute oral toxicity (LD50): 3310 mg/kg [Rat]. Acute dermal toxicity (LD50): 1060 mg/kg [Rabbit]. Acute toxicity of the vapor (LC50): 5620 1 hours [Mouse].
Chronic Effects on Humans:
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast. May cause damage to the following organs: kidneys, mucous membranes, skin, teeth.
Other Toxic Effects on Humans: Extremely hazardous in case of inhalation (lung corrosive). Very hazardous in case of skin contact (irritant), of ingestion, Hazardous in case of skin contact (corrosive, permeator), of eye contact (corrosive).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material and may cause reproductive effects based on animal data. No human data found.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: Extremely irritating and corrosive. Causes skin irritation (reddening and itching,
inflammation). May cause blistering, tissue damage and burns.
Eyes: Extremely irritating and corrosive. Causes eye irritation, lacrimation, redness, and
pain. May cause burns, blurred vision, conjunctivitis, conjunctival and corneal
destruction and permanent injury.
Inhalation: Causes severe respiratory tract irritation. Affects the sense organs (nose,
ear, eye, taste), and blood. May cause chemical pneumonitis, bronchitis, and
pulmonary enema. Severe exposure may result in lung tissue damage and corrosion
(ulceration) of the mucous membranes. Inhalation may also cause rhinitis, sneezing,
coughing, oppressive feeling in the chest or chest pain, dyspnoea, wheezing,
tachypnoea, cyanosis, salivation, nausea, giddiness, muscular weakness.
Ingestion: Moderately toxic. Corrosive. Causes gastrointestinal tract irritation (burning
and pain of the mouth, throat, and abdomen, coughing, ulceration, bleeding, nausea,
abdominal spasms, vomiting, hematemesis, diarrhea. May Also affect the liver (impaired liver function), behaviour (convulsions, giddiness, muscular weakness), and the urinary system – kidneys (Haematuria, Albuminuria, Nephrosis, acute renal failure, acute tubular necrosis). May also cause dyspnoea or asphyxia. May also lead to shock, coma and death.
Chronic Potential Health Effects: Chronic exposure via ingestion may cause blackening or erosion of the teeth and jaw necrosis, pharyngitis, and gastritis. It may also behaviour (like acute ingestion), and metabolism (weight loss). Chronic exposure via inhalation may cause asthma and/or bronchitis with cough, phlegm, and/or shortness of breath. It may also affect the blood (decreased leukocyte count), and urinary system (kidneys). Repeated or prolonged skin contact may cause thickening, blackening, and cracking of the skin.
12: Ecological Information
Ecotoxicity: Ecotoxicity in water (LC50): 423 mg/l 24 hours [Fish (Goldfish)]. 88 ppm 96 hours [Fish (fathead minnow)]. 75 ppm 96 hours [Fish (bluegill sunfish)]. >100 ppm 96 hours [Daphnia].
BOD5 and COD: BOD-5: 0.34-0.88 g oxygen/g
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
14: Transport Information
CLASS 3: Flammable liquid. Class 8: Corrosive material
Identification: Acetic Acid, Glacial UNNA: 2789 PG: II
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Protective Equipment: Gloves (impervious). Synthetic apron. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate. Splash goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
EXCLUSION OF LIABILITY
All information and instructions provided in this Material Safety Data Sheet in respect of the substance is given solely in terms of the provisions of the Occupational Health and Safety Act No 85 of 1993
and Regulations (“the Act”), is based on scientific and technical knowledge as at the date indicated on this MS Material Safety Data Sheet and is presented in good faith to be correct.
The information and instructions provided in this MSDS apply only to the substance in its present form and not to any formulation or mix, in which event it is the sole responsibility of the user of the substance as formulated and/or mixed to investigate and establish any danger which may arise out of its use, wherever such user may be situated.
It is the sole responsibility of the person in receipt of this Material Safety Data Sheet wherever such recipient may be situated, to ensure that the information provided is communicated to and understood by any person who may come in contact with the substance in any place and in any manner whatsoever. If such recipient produces formulations or mixes using the substance, then it is such recipient’s sole responsibility to comply with the provisions of the Act in respect of the provision of the necessary Material Safety Data Sheet, or to comply with any other applicable legislation.