1: Chemical Product Identification

Product Name: Ethylenediaminetetraacetic Acid
Tetrasodium Salt
Catalogue Codes: SLE2284
CAS#: 10378-23-1
RTECS: AH5075000 (For CAS no. 64-02-8 known as
EDTA Tetrasodium salt, anhydrous)
TSCA: TSCA 8(b) inventory: No products were found.
CI#: Not available.
Synonym: Versene, Kalex, Hampene, Dissolvine; EDTA tetrasodium salt dihydrate; Tetrasodium EDTA dihydrate; Tetrasodium salt EDTA dihydrate; Tetrasodium salt of EDTA, dihydrate; Tetrasodium salt of ethylenediaminetetraacetic acid, dihydrate; Sodium salt of ethylenediaminetetraacetic acid, dihydrate; Sodium ethylenediaminetetraacetate, dihydrate; Sodium ethylenediaminetetraacetic acid, dihydrate; Sodium EDTA, dihydrate; Edetate sodium dihydrate; Edetic acid tetrasodium salt, dihydrate; Endrate tetrasodium; Ethylenebis(iminodiacetic acid) tetrasodium salt, dihydrate; Ethylenediaminetetraacetic acid, tetrasodium salt, dihydrate; Edathaniltetrasodium, dihydrate; N, N’-Ethylenediaminediacetic acid tetrasodium salt. Chemical Name: Acetic acid, (etrhylenedinitrilo)tetra-tetrasodium salt, dihydrate
Chemical Formula: C10H12N2Na4O8.2H2O

2. Composition and Information on Ingredients 

3: Hazards Identification

Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation.

Potential Chronic Health Effects:




DEVELOPMENTAL TOXICITY: Not available. The substance may be toxic to upper

respiratory tract, skin, eyes. Repeated or prolonged exposure to the substance can produce target organs damage.

4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.

Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used.

Serious Skin Contact: Not available.

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.

Serious Inhalation: Not available.

Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.

Serious Ingestion: Not available.

5: Fire and Explosion Data

Flammability of the Product:                                                       May be combustible at high temperature.

Auto-Ignition Temperature:                                                        Not available.

Flash Points:                                                                                       CLOSED CUP: Higher than 93.3°C (200°F).

Flammable Limits:                                                                            Not available.

Products of Combustion:                                                              These products are carbon oxides (CO, CO2),

nitrogen oxides (NO, NO2…). Some metallic oxides.

Fire Hazards in Presence of Various Substances:                 Slightly flammable to flammable in presence

of heat. Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances:     Slightly explosive in presence of open flames

and sparks. Nonexplosive in presence of shocks.

Fire Fighting Media and Instructions:                                       SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards:                                              As with most organic solids, fire is possible

at elevated temperatures

Special Remarks on Explosion Hazards:                                   Fine dust dispersed in air in sufficient

concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. If necessary: Neutralize the residue with a dilute solution of acetic acid. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.

Large Spill: Use a shovel to put the material into a convenient waste disposal container. Neutralize the residue with a dilute solution of acetic acid. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

7: Handling and Storage

Precautions:  Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, metals.

Storage:  Keep container tightly closed. Keep container in a cool, well-ventilated area.

8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne

levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.

Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

Exposure Limits: Not available.

9: Physical and Chemical Properties

Physical state and appearance:                                                  Solid. (Crystalline solid.)

Odour:                                                                                                  Not available.

Taste:                                                                                                    Not available.

Molecular Weight:                                                                           416.23 g/mole

Colour:                                                                                                 White.

pH (1% soln/water):                                                                        11.3 [Basic.]

Boiling Point:                                                                                     Not available.

Melting Point:                                                                                    Not available.

Critical Temperature:                                                                     Not available.

Specific Gravity: Bulk Density:                                                     0.77 (Water = 1)

Vapor Pressure:                                                                                Not applicable.

Vapor Density:                                                                                   Not available.

Volatility:                                                                                             Not available.

Odour Threshold:                                                                             Not available.

Water/Oil Dist. Coeff.:                                                                   Not available.

Iconicity (in Water):                                                                         Not available.

Dispersion Properties:                                                                    See solubility in water.

Solubility:                                                                                           Soluble in cold water.

10: Stability and Reactivity Data

Stability:                                                                                               The product is stable.

Instability Temperature:                                                               Not available.

Conditions of Instability:                                                               Not available.

Incompatibility with various substances:                                Reactive with oxidizing agents, metals.

Corrosivity:                                                                                         Non-corrosive in presence of glass.

Special Remarks on Reactivity:                                                    Avoid contact with aluminium, copper,

copper alloys, zinc, and nickel, and strong oxidizers.

Special Remarks on Corrosivity:                                                  Not available.

Polymerization:                                                                                                Will not occur.

11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): >2000 mg/kg [Rat].

Chronic Effects on Humans: May cause damage to the following organs: upper respiratory tract, skin, eyes.

Other Toxic Effects on Humans: Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Acute Potential Health effects:

Skin: May cause skin irritation.

Eyes: May cause eye irritation. Inhalation: May cause irritation of the respiratory tract. Ingestion: May cause gastrointestinal tract irritation. The toxicological properties of this substance have not been fully investigated.

12: Ecological Information

Ecotoxicity: Ecotoxicity in water (LC50): 760 mg/l 96 hours [Bull gill sunfish]. 59.8 mg/l 96 hours [Fathead Minnow].

BOD5 and COD: Not available.

Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.

Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Special Remarks on the Products of Biodegradation: Not available.

13: Disposal Considerations

Waste Disposal:  Waste must be disposed of in accordance with federal, state and local environmental control regulations.

14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

15: Other Regulatory Information

Other Regulations: OSHA: Hazardous of Hazard Communication Standard (29 CFR 1910.1200).

Protective Equipment: Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses.

16: Other Information

References: Not available.

Other Special Considerations: Not available.


All information and instructions provided in this Material Safety Data Sheet in respect of the substance is given solely in terms of the provisions of the Occupational Health and Safety Act No 85 of 1993

and Regulations (“the Act”), is based on scientific and technical knowledge as at the date indicated on this MS Material Safety Data Sheet and is presented in good faith to be correct.

The information and instructions provided in this MSDS apply only to the substance in its present form and not to any formulation or mix, in which event it is the sole responsibility of the user of the substance as formulated and/or mixed to investigate and establish any danger which may arise out of its use, wherever such user may be situated.

It is the sole responsibility of the person in receipt of this Material Safety Data Sheet wherever such recipient may be situated, to ensure that the information provided is communicated to and understood by any person who may come in contact with the substance in any place and in any manner whatsoever. If such recipient produces formulations or mixes using the substance, then it is such recipient’s sole responsibility to comply with the provisions of the Act in respect of the provision of the necessary Material Safety Data Sheet, or to comply with any other applicable legislation.